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LyoPharm

From 4.3 to 45 m² of shelf area
Condenser capacity up to 820 kg
Output for 2R up to 190,440 vials

GMP production equipment

Standardized configuration of chamber, condenser, cooling and vacuum systems


External condenser connected by mushroom valve


Side or front maintenance door


  • GMP freeze dryers
  • GMP freeze dryers
  • GMP freeze dryers
  • GMP freeze dryers
  • GMP freeze dryers
  • GMP freeze dryers

Freeze dryers within everyone’s reach. Outstanding standarization.

LyoPharm is an excellent example of the balance between the investment made and benefits obtained.

Dara-Lyo has designed and standardized the best configuration for each vial dimension to offer high-performance equipment at affordable prices.

Additionally, the standardization of its components and configu-rations allows us to manufacture LyoPharm with reduced delivery times.

Model LyoPharm
Shelf area 4.32 m² 5.04 m² 5.76 m² 7.2 m² 8.64 m² 10.08 m² 11.52 m² 12.96 m² 14.4 m²
Shelf dimensions (W x D) 800 x 900 mm 1,200 x 1,200 mm
Nº of shelves 6 + 1 7 + 1 8 + 1 5 + 1 6 + 1 7 + 1 8 + 1 9 + 1 10 + 1
Shelves clearance 105 mm 90 mm 75 mm 105 mm 90 mm 75 mm 105 mm 90 mm 75 mm
Chamber width 1,750 mm 2,200 mm
Chamber height 3,500 mm 3,800 mm 4,200 mm
Condenser capacity 115 kg 190 kg 275 kg
Tray dimensions 300 x 400 mm
Condenser temperature -75 ºC
Shelves temperature range from -55 ºC to +85 ºC
Modelo LyoPharm
Shelf area 16.8 m² 19.2 m² 21.6 m² 24 m² 26.4 m² 28.8 m² 31.2 m² 33.6 m² 36 m² 39 m² 42 m² 45 m²
Shelf dimensions (W x D)  1,500 x 1,600 mm 1,500 x 2,000 mm
Nº of shelves 7 + 1 8 + 1 9 + 1 10 + 1 11 + 1 12 + 1 13 + 1 14 + 1 15 + 1 13 + 1 14 + 1 15 + 1
Shelves clearance 105 mm 90 mm 75 mm 105 mm 90 mm 75 mm 105 mm 90 mm 75 mm 105 mm 90 mm 75 mm
Chamber width 2,600 mm
Chamber height 3,800 mm 4,200 mm 4,600 mm 5,000 mm
Condenser capacity 410 Kg 550 Kg 685 Kg 820 Kg
Tray dimensions 300 x 400 mm
Condenser temperature -75 ºC
Shelves temperature range from -55 ºC to +85 ºC

Optional equipment

The chamber

  • Pressureless vessel

  • Cooling by cold water or silicone circuit

Connection with condenser

  • Butterfly valve

  • Mushroom valve

  • Bottom shelf closing

Ice condenser

  • Integrated underneath, on the same floor

  • Integrated on the side, on the same floor

  • Outside, behind the camera, on the same floor

  • Outside, under the camera, on another floor

Shelf movement

  • Closing system hydraulic piston

  • Bellows

  • Connection with automatic charging system

CIP

  • Chamber and condenser cleaning system

  • Recirculation system with heating and/or detergent addition

  • Multiple cleaning cycles

  • CIP independent skid

SIP

  • PED

  • ASME

  • Chamber cool-down after SIP

Plant distribution

  • 1st floor

  • 2 floors

  • Passthrough system

  • Standalone frames

Additional elements

  • ATEX (processes with solvents and/or alcohol)

  • Cold tray loading

  • Frozen tray loading

  • Nucleation technology

Refrigeration

  • Piston compressor

  • Screw compressor

  • Cascade system

  • Liquid nitrogen system

  • Cooling system without PCA

  • Natural gases system

Door

  • Full size door

  • Automatic locking

  • Slot front door (constant loading level)

  • Full size sub-door

  • Cooling by cold water circuit

Process sensors

  • Pirani

  • Capacitive

  • Temperature probes (Pt-100 / Thermocouple)

  • Redundant temperature probes (Pt-100 / Thermocouple)

  • Wireless temperature monitoring

  • Full batch traceability software

  • PAT tools

Control systems

  • Rockwell / Siemens Automation PLC

  • Integrated HMI

  • SCADA

  • Electronic recorder

  • Electronic Server and Think Client

  • Cycle optimization technology

Filter vent system

  • Sterilizable

  • Ports for integrity testing

  • Secondary venting cycle

  • Secondary vent filter

  • Water filter integrity test

Vacuum system

  • Double stage rotary vane pumps

  • Redundancy (additional pump)

  • Dry pumps

  • Roots pumps

Always at your disposal!

We look forward to assisting you with your projects and answering your questions and suggestions. Fill in this form and we will contact you as soon as possible.

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