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LyoPro

From 16.8 to 45 m² of shelf area
Condenser capacity up to 820 kg
Output for 2R up to 190,440 vials

GMP production equipment for large scale production

External condenser in 1 or 2 floor configuration


Mushroom valve as intermediate valve


Continuous circular coil in condenser


Standalone frame for cooling system


Standalone frame for vacuum system


  • GMP freeze dryers for large production scale
  • GMP freeze dryers for large production scale
  • GMP freeze dryers for large production scale
  • GMP freeze dryers for large production scale
  • GMP freeze dryers for large production scale
  • GMP freeze dryers for large production scale

Maximum performance. Large-scale security and reliability.

Do you need a high-performance freeze dryer for large scale production?

Dara-Lyo offers a solution for this requirement, our LyoPro model. This freeze dryer enables safe, large-scale freeze drying, has been designed for easy installation, and has maximum flexibility. As the flagship of the Dara-Lyo family of freeze-dryers, the LyoPro range has been designed to feature precise control, in order to manage large batch freeze drying with the same efficiency and exactness as that of small batches.

With cooling and vacuum systems that are compact in size, and built from the highest quality materials, this model is unrivaled in quality and capability.

Model LyoPro
Shelf area 16.8 m² 19.2 m² 21.6 m² 24 m² 26.4 m² 28.8 m² 31.2 m² 33.6 m² 36 m² 39 m² 42 m² 45 m²
Shelf dimensions (W x D) 1,500 x 1,600 mm 1,500 x 2,000 mm
Nº of shelves 7 + 1 8 + 1 9 + 1 10 + 1 11 + 1 12 + 1 13 + 1 14 + 1 15 + 1 13 + 1 14 + 1 15 + 1
Shelves clearance 105 mm 90 mm 75 mm 105 mm 90 mm 75 mm 105 mm 90 mm 75 mm 105 mm 90 mm 75 mm
Chamber width 2,600 mm
Chamber height 3,800 mm 4,400 mm 4,600 mm 5,000 mm
Condenser capacity 410 Kg 550 Kg 685 Kg 820 Kg
Condenser temperature -75 ºC
Shelves temperature range from -55 ºC to +85 ºC

Optional equipment

The chamber

  • Pressureless vessel

  • Cooling by cold water or silicone circuit

Connection with condenser

  • Butterfly valve

  • Mushroom valve

  • Bottom shelf closing

Ice condenser

  • Integrated underneath, on the same floor

  • Integrated on the side, on the same floor

  • Outside, behind the camera, on the same floor

  • Outside, under the camera, on another floor

Shelf movement

  • Closing system hydraulic piston

  • Bellows

  • Connection with automatic charging system

CIP

  • Chamber and condenser cleaning system

  • Recirculation system with heating and/or detergent addition

  • Multiple cleaning cycles

  • CIP independent skid

SIP

  • PED

  • ASME

  • Chamber cool-down after SIP

Plant distribution

  • 1st floor

  • 2 floors

  • Passthrough system

  • Standalone frames

Additional elements

  • ATEX (processes with solvents and/or alcohol)

  • Cold tray loading

  • Frozen tray loading

  • Nucleation technology

Refrigeration

  • Piston compressor

  • Screw compressor

  • Cascade system

  • Liquid nitrogen system

  • Cooling system without PCA

  • Natural gases system

Door

  • Full size door

  • Automatic locking

  • Slot front door (constant loading level)

  • Full size sub-door

  • Cooling by cold water circuit

Process sensors

  • Pirani

  • Capacitive

  • Temperature probes (Pt-100 / Thermocouple)

  • Redundant temperature probes (Pt-100 / Thermocouple)

  • Wireless temperature monitoring

  • Full batch traceability software

  • PAT tools

Control systems

  • Rockwell / Siemens Automation PLC

  • Integrated HMI

  • SCADA

  • Electronic recorder

  • Electronic Server and Think Client

  • Cycle optimization technology

Filter vent system

  • Sterilizable

  • Ports for integrity testing

  • Secondary venting cycle

  • Secondary vent filter

  • Water filter integrity test

Vacuum system

  • Double stage rotary vane pumps

  • Redundancy (additional pump)

  • Dry pumps

  • Roots pumps

Always at your disposal!

We look forward to assisting you with your projects and answering your questions and suggestions. Fill in this form and we will contact you as soon as possible.

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